Both groups performed 10 sets of 10 maximal eccentric repetitions of single-leg extension on the Cybex dynamometer at 60°/s with 20-s rest periods between sets. Fourteen postmenopausal women were divided into two groups: women not using HT (control n = 6, 59 ± 4 yr, 63 ± 17 kg) and women using traditional HT (HT n = 8, 59 ± 4 yr, 89 ± 24 kg). We evaluated changes in markers of exercise-induced skeletal muscle damage and inflammation in postmenopausal women after a high-intensity resistance exercise bout. Hormone therapy (HT) is a potential treatment to relieve symptoms of menopause and prevent the onset of disease such as osteoporosis in postmenopausal women.
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